Name | 1,4-Piperazinebis(ethanesulphonic acid) |
Synonyms | PIPES MOLYBDENE STAND MOLYBDENUM STAND TIMTEC-BB SBB008973 LABOTEST-BB LT00138111 PIPES, Free Acid, ULTROL Grade 1,4-PIPERAZINEDIETHANESULFONIC ACID PIPES, Free Acid, MB Grade (1.12030) PIPES BIOXTRA, FOR MOLECULAR BIOLOGY ABTS DIAMMONIUM SALT ULTRA PURE GRADE Piperazine-1,4-bisethanesulfonic acid 1,4-Piperazinebis(ethanesulfonic acid) 1,4-Piperazinebis(ethanesulphonic acid) PIPERAZINE-NN'-BIS-2-ETHANESULPHONIC ACID Piperazine-1,4-bis(2-ethanesulfonic acid) Piperazine-N,N'-bis(2-ethanesulfonic acid) PIPES Piperazine-1,4-bisethanesulfonic acid PIPES Piperazine-N,N-bis(2-ethanesulfonic acid) 2,2-(piperazine-1,4-diyl)bis(ethanesulphonic) acid PIPES, Molecular Biology Grade Piperazine-N,N-bis(2-ethanesulfonic acid), Molecular Biology Grade |
CAS | 5625-37-6 |
EINECS | 227-057-6 |
InChI | InChI=1/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16) |
InChIKey | XWGRYGKFRRLUQQ-UHFFFAOYSA-N |
Molecular Formula | C8H18N2O6S2 |
Molar Mass | 302.37 |
Density | 1.4983 (rough estimate) |
Melting Point | >300 °C (lit.) |
Boling Point | 1·505 |
Water Solubility | Soluble in water. |
Solubility | Soluble in 1M NaOH (0.5 M at 20 °C), water (~1 g/L at 100 °C), and 0.5 N NaOH (0. |
Appearance | White powder |
Color | White |
Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.055', , 'λ: 280 nm Amax: 0.040'] |
Merck | 14,7479 |
BRN | 817713 |
pKa | 6.8(at 25℃) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.6300 (estimate) |
MDL | MFCD00006159 |
Use | Hybrid selection of mRNA-pre-hybrid buffer components. |
In vitro study | To prepare the pH PIPES buffer, 173 g of 1,4-piperazinediethanesulfonic acid are dissolved into 1 L of deionized water. The pH of the PIPES buffer is adjusted to 6.8 by adding pellets of sodium hydroxide. PIPES buffer can be used to PIPES buffer, it can prevent the glutaraldehyde fixation induced lipid loss and artifacts. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 29335995 |
Reference Show more | 1. Zhao, Xinxin, et al. "Influence of lard-based diacylglycerol on rheological and physicochemical properties of thermally induced gels of porcine myofibrillar protein at different NaCl concentrations." Food Research International 127 (2020): 108723.https://d |
pH range of acid-base indicator discoloration | 6.1 - 7.5 |
LogP | -2.7 at 20℃ |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Application | piperazine-N,N-bis (2-ethanesulfonic acid) is used as a biological buffer, can be used in laboratory research and development process and chemical production process. |
biological activity | PIPES (1, 4-pipeazinediethanesulfonic acid) is an important component of PIPES buffer and is commonly used as a Biochemical reagent. |
Use | biological buffer |